报 告 内 容 简 介 | 报告人简介：Katarina Svanberg is an M.D. and a Ph.D., and has been working as a clinical doctor as well as an associated professor in Oncology at Lund University, Sweden and as a distinguished professor at South China Normal University, Guangzhou. She has been director and later chairperson of the board for the Lund Medical Laser Centre. During a period of more than ten years she was on the board of the International Society of Optics and Photonics (SPIE), was in its presidential chain for four years and also serving as the president of the society. She received the US National Institute of Health (NIH) Award for Translational Efforts to take optical techniques from the lab bench to the patients. Among other prizes, she was also the recipient of the SPIE Gold medal. Her main research interests are within the field of laser applications in medicine. She has several patents and patent applications and helped forming spin-off companies.
报告内容简介：Laser spectroscopy has been shown to be a valuable tool both in the detection and the therapy of human malignancies. The most important prognostic factor for cancer patients is early tumor discovery. If malignant tumors are detected during the non-invasive stage, most tumors show a high cure rate of more than 90 %. Even though there are many conventional diagnostic modalities, very early tumors may be difficult to discover. Laser-induced fluorescence (LIF) for tissue characterization is a technique that can be used for early monitoring the biomolecular changes. Photodynamic therapy is a selective treatment technique for human malignancies. To overcome the limited light penetration in superficial illumination, interstitial delivery (IPDT) with the light transmitted to the tumor via optical fibers has been developed. Interactive feed-back dosimetry is of importance for optimizing this modality and such a concept will be described. Another technique which has been developed for medical application, is based on gas in scattering media absorption spectroscopy (GASMAS). The technique is used to detect free gas (e.g., oxygen and water vapor) in hollow organs in the human body and has been applied to the detection of inflammation in the human sinus cavities and in the middle ear in small kids. A certain proportion of these infections are virally induced, and in these cases no antibiotics should be prescribed. GASMAS has a potential to discriminate the origin of the disease and thus guide in the decision of appropriate therapy, trying to fight the global problem of antibiotic resistance. The GASMAS technique can also be used for lung surveillance of prematurely born infants, and in that way help them to survive. Such techniques are now being extended towards larger children and adults affected by serious lung problems. |
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